New ways to deal with excessive weight gain in patients treated with antipsychotics

Credit: Unsplash / CC0 Public Domain

New research led by Dr. Gurkiran Birdi and Dr. Ian Maidment of the College of Health and Life Sciences at Aston University will explore ways to deal with excessive weight gain in patients treated with antipsychotics for mental illnesses such as schizophrenia.

The project, known as RESOLVE, will study non-pharmacological interventions for antipsychotic-induced weight gain in people living with severe mental illness (SMI) by working directly with patients to understand and explain how, why, for whom and in what contexts non-pharmacological interventions can help service users cope with antipsychotic-induced weight gain.

Antipsychotics are widely used in the treatment of schizophrenia and other serious mental illnesses (SMI). Over the last 20 years, the first generation of antipsychotics has been replaced by the newer second generation of antipsychotics. There are over 220,000 people being treated for schizophrenia in the UK at any given time.

Up to 80% of people with schizophrenia or bipolar disorder are overweight or obese. Weight increases of up to 33 kg has been reported with antipsychotics. This weight gain has devastating consequences: Life expectancy is reduced by 20 years in people with schizophrenia, partly related to the consequences of this weight gain. Diabetes has been reported to be a major problem with second-generation antipsychotics.

Also Read:  Would more labeling really help us eat less sugar?

In RESOLVE – which includes partners from the University of East Anglia, Oxford, Cambridge, Birmingham Universities, the NHS and the McPin Foundation – researchers will combine literature on what has been written on the subject. The team will also interview volunteers, both people who have suffered from weight loss and health professionals involved, to understand their lived experience of weight gain. We also want to find out what works to help control weight.

At the end of the project, the team plans to develop guidance for users and therapists on the best ways to treat and manage weight gain.

Dr. Ian Maidment, a reader in clinical pharmacy and lead researcher, said: “Before I moved to academia, I spent 20 years working in mental health services. This is a really important topic, I have seen patients literally” balloon “weight with their weight rising from 80 to 120 kg. We need to find better ways to help them. “

A member of the RESOLVE Lived Experience Advisory Group said: “The RESOLVE study could provide a tailored solution to my antipsychotic weight gain that could benefit my unique needs as an individual. I have found that weight gain by taking antipsychotics has been a real health problem “I find that this is often ignored or stigmatized by friends, family and healthcare professionals. In addition, there does not seem to be any solution available that works at the moment.”

Also Read:  Global Variations in Preoperative Practice in Patients Desiring Primary Bariatric and Metabolic Surgery (PACT Study): A Survey of 634 Bariatric Health Care Professionals

How does weight gain from antipsychotic medication affect patients? Provided by Aston University

Quote: New Ways to Deal With Excessive Weight Gain in Patients Treated with Antipsychotics (2022, April 15,) Retrieved April 17, 2022 from https://medicalxpress.com/news/2022-04-ways-excessive-weight-gain- patients. html

This document is subject to copyright. Except for any reasonable trade for the purpose of private investigation or research, no part may be reproduced without written permission. The content is provided for informational purposes only.

Leave a Reply

Your email address will not be published.